Research at the Physics and Astronomy department is focused around five main themes:
- Physics of Life
- Physics of Energy
- Fundamental Physics
- Physics of Nanolithography
- Science, Business and Innovation
The department is involved in teaching in the programs Physics and Astronomy (joint degree with the University of Amsterdam), Science Business and Innovation, Medical Natural Sciences (all three BSc and MSc), and the BSc program in Mechanical Engineering (together with University of Twente).