The bacterial cell envelope separates bacteria from the environment and therefore plays a central role in the interaction of these organisms with the outside world. Bacteria have to keep their cell envelope as impermeable as possible to protect their internal milieu against toxic agents from the environment. However, they also have to take up nutrients and secrete macromolecules across this cell envelope for growth, communication and virulence. The aim of our research is to better understand the mechanisms by which bacteria unite these contrasting requirements. Importantly, we also use the gained knowledge for biotechnological and medical innovations such as the development of antibiotics and vaccines.
Molecular Microbiology has three main research themes:
- Protein trafficking in Gram-negative and Gram-positive bacteria
- Dr. Joen Luirink
- Dr. Peter van Ulsen
- Cell envelope processes of pathogenic mycobacteria
- Prof. Wilbert Bitter
- Dr. Edith Houben
- Discovery of antibiotics targeting the bacterial cell envelope and bacterial metabolism
- Prof. Wilbert Bitter
- Dr. Dirk Bald
- Dr. Joen Luirink
- Dr. Peter van Ulsen