In this theme, we focus on protein trafficking in bacteria. In particular, we examine insertion, folding and assembly of membrane proteins in both the cytoplasmic and outer membrane of the bacterial cell envelope.
In addition, we study trans-envelope transport via the type V secretion system, a route that is taken by many virulence factors of Gram-negative pathogenic bacteria. Our fundamental research is aimed at elucidating mechanistic details at the molecular level, but we also have a keen eye for applicable spin-offs, which includes the development of approaches to secrete recombinant proteins in biotech production processes.