Group page: David Dulin lab – Biological Physics of Gene Machines
David Dulin graduated his PhD at the Institut d’Optique-University Paris-Saclay on investigating bacterial and mammalian ribosome elongation dynamics using single-molecule fluorescence microscopy. He continued his academic journey in single-molecule biophysics by doing a first postdoc at TU Delft (The Netherlands) and a second one at the University of Oxford (England). He then started his lab in Germany at FAU Erlangen-Nuremberg, where he was the “Physics and Medicine” IZKF junior group leader. In 2021, he relocated his lab at the Vrije Universiteit Amsterdam where he currently is an assistant professor. He pioneered high-throughput and high-spatiotemporal resolution magnetic tweezers, and the investigation of RNA virus replication/transcription in vitro at the single-molecule level. He established the first single-molecule assay to investigate the SARS-CoV-2 replication-transcription complex RNA synthesis dynamics, which he applied to reveal one mechanism of action of the antiviral Remdesivir. He has been awarded several grants from the German Research foundation (DFG), the Dutch Research Council (NWO), and the National Institutes of Health (NIH).
