Research Description
We combine optical imaging with computational techniques. While some optical imaging techniques are only possible by using appropriate algorithms, others benefit from them by improving resolution, image quality, or cost-effectiveness. We develop these methods and apply them in biomedicine. For example, we research computational methods for optical coherence tomography (OCT) and their applications. Using a dedicated full-field Fourier-domain OCT system, we achieve record-breaking acquisition rates of up to 100 million depth scans (A-scans) per second, reducing motion artifacts and allowing us to use the phase of the light for image reconstruction and for additional contrast. This capability also permits label-free observation of microscopic structural and functional changes in retinal cells, such as photoreceptors and neurons, following light stimulation.
