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PhD defence M.E. de Leeuwerk 5 February 2026 13:45 - 15:15

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Optimizing physical recovery after oncological surgery

Digital support accelerates recovery after cancer surgery

Patients recover faster and more effectively from major cancer surgery when they receive digital support for nutrition and physical activity at home. This is shown by research conducted by physiotherapist Marijke de Leeuwerk into the OPRAH intervention (Optimal Physical Recovery After Hospitalization), a program that provides remote support to patients using an app, an activity sensor, and coaching by a physiotherapist and dietitian.

Major cancer surgery often has profound effects on the body. Many patients lose muscle mass and strength, experience severe fatigue, and struggle with daily activities. Previous research shows that a substantial proportion of patients have not fully recovered even three to six months after surgery. Although patients receive guidance on nutrition and physical activity in the hospital, this support largely disappears after discharge.

De Leeuwerk’s research focused on closing this gap in care. The OPRAH intervention that was developed provided patients with additional support at home. Through an app and an activity sensor, patients gained insight into their daily physical activity, while healthcare professionals provided remote coaching and advice on exercise and protein intake.

The results show that this approach is effective. Patients who participated in the intervention were more physically active, more often met their protein requirements, and reported less fatigue than patients without digital support. Their physical functioning also recovered better. According to De Leeuwerk, sufficient physical activity and protein intake are essential for maintaining and rebuilding muscle after surgery.

Digital support makes it possible for patients to work safely and independently on their recovery at home, while still receiving personalized, tailored support from healthcare professionals. This reduces the need for additional hospital visits and aligns with the growing pressure on healthcare systems and ongoing staff shortages.

The study therefore highlights the potential of digital healthcare solutions to improve postoperative recovery while keeping healthcare accessible, efficient, and affordable.

More information on the thesis

Programme

PhD defence by M.E. de Leeuwerk

PhD Faculty of Medicine

Supervisors:

  • dr. M. van der Leeden
  • dr. M. van der Schaaf
  • prof.dr. V. de Groot

The PhD defence can be followed online as well

About PhD defence M.E. de Leeuwerk

Starting date

  • 5 February 2026

Time

  • 13:45 - 15:15

Location

  • VU Main Building

Address

  • De Boelelaan 1105
  • 1081 HV Amsterdam

Follow the defence online

Go to livestream

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