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PhD defence K.J. Nelissen 10 June 2025 15:45 - 17:15

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CBCT-guided online adaptive radiotherapy: a novel approach for breast and fast palliative treatments

Researcher Koen Nelissen has developed an innovative method using online adaptive radiotherapy that significantly speeds up the treatment process while making it more patient-friendly. In traditional radiotherapy, patients often have to wait several days due to time-consuming preparation, including separate scans and planning procedures. Nelissen’s approach allows for immediate treatment. This is especially beneficial for patients in palliative care, who benefit from swift procedures and minimal hospital visits.

Nelissen explored an alternative method for treating palliative patients with (bone) metastases, utilizing existing imaging and online adaptive radiotherapy. This makes it possible to complete both the first in-person consultation with the physician and the treatment itself within two hours. This method was implemented and evaluated in the FAST-METS study. Results show that the treatment is well-tolerated and that factors such as the patient's physical condition and the location of the target area influence the treatment duration.

In addition to palliative care, a similar approach was studied in breast cancer patients as part of the BREAST-ART study. This research demonstrated that online adaptive radiotherapy is also effective in this group and that in many cases, no interim adjustments to the treatment plan are needed. This approach contributes to improved patient care and reduces the strain on healthcare processes.

More information on the thesis

Programme

PhD defence by K.J. Nelissen

PhD Faculty of Medicine

Supervisors:

  • prof.dr. S. Senan
  • prof.dr. B.J. Slotman
  • dr.ir. W.F.A.R. Verbakel

The PhD defence can be followed online as well

About PhD defence K.J. Nelissen

Starting date

  • 10 June 2025

Time

  • 15:45 - 17:15

Location

  • Auditorium, Main building
  • (1st floor)

Address

  • De Boelelaan 1105
  • 1081 HV Amsterdam

Follow the defence online

Go to livestream

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