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PhD defence B.M.A. Gonggrijp 24 March 2025 11:45 - 13:15

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Invisible Scars

The impact of victimization on health

Victimization is associated with both mental health issues and biological ageing. The explanation for this relationship is complex. In addition to the direct impact of these events, genetic and environmental factors also play a role. This is the result of the doctoral research of behavioural geneticist Bodine Gonggrijp.

Being a victim of a violent crime—or another traumatic event—can leave deep physical and mental scars. Behavioural geneticist Bodine Gonggrijp investigated the relationship between victimization, mental health issues, and biological processes at VU Amsterdam.

‘My research shows that victimization is often linked to mental health problems such as depression, anxiety, and loneliness,’ says Gonggrijp. ‘I specifically examined experiences of crime, including violent offences, sexual assaults, and thefts. Victimization can also influence epigenetic processes, such as an accelerated ageing process in the body.’ She concludes that these effects are not solely caused by victimization itself but are also influenced by genetic predisposition and environmental factors.

Twins as research model
To explore this, Gonggrijp studied twin pairs participating in the Netherlands Twin Register at VU Amsterdam. ‘By comparing twin pairs in which one has been a victim and the other has not, I was able to distinguish between the direct consequences of victimization and the effects of genetic or environmental factors,’ she explains.

Gonggrijp concludes that individuals who are already vulnerable, for instance due to psychological issues, have a higher likelihood of becoming victims. This aligns with previous research findings: perpetrators often try to minimise the risks of their actions by targeting individuals perceived as vulnerable. ‘This means it is important not only to examine the consequences of victimization  but also to consider factors that can increase a person’s vulnerability,’ Gonggrijp states.

Biological ageing
Gonggrijp studied biological ageing in people who have experienced severe negative events (including victimization) using epigenetic biomarkers. Several such biomarkers have been developed to measure biological age. ‘In my research, I found that significant life events, such as financial difficulties and sexual victimhood, were particularly associated with an accelerated ageing process, as measured by epigenetic age indicators,’ says Gonggrijp.

These associations remained even after adjusting for factors such as smoking and body mass index (BMI). However, comparisons within discordant twin pairs suggest that genetic and shared environmental factors may also play a role in this relationship, highlighting the complexity of the link between victimization  and accelerated ageing.

Practical implications
Gonggrijp hopes her research will contribute to a better understanding of the impact of victimization and the mechanisms involved. ‘By taking genetic and environmental influences into account, we can better understand why some people are more vulnerable than others,’ she says. This could provide valuable insights for professionals and policymakers, for example, in developing preventive interventions and targeted support for at-risk groups.

More information on the thesis

Programme

PhD defence by B.M.A. Gonggrijp

PhD Faculty of Behavioural and Movement Sciences

Supervisors:

  • prof.dr. D.I. Boomsma
  • prof.dr. C.C.J.H. Bijleveld
  • dr. J. van Dongen
  • dr. S. van de Weijer

The PhD defence can be followed online as well

About PhD defence B.M.A. Gonggrijp

Starting date

  • 24 March 2025

Time

  • 11:45 - 13:15

Location

  • Auditorium, Main building
  • (1st floor)

Address

  • De Boelelaan 1105
  • 1081 HV Amsterdam

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