The course aims at providing knowledge of concepts of Molecular Neurobiology in the context of investigating and understanding gene function in the nervous system.
Course Objective
- General introduction to molecular biological principles
- Various quantification methods (e.g. quantitative PCR, Western blotting)
- Screening techniques (hybridization, micro arrays, SAGE, deep sequencing)
- Structure-function research (mutagenesis, 3D structure analysis)
- Genetic intervention studies (viral vectors, transgenesis, RNAi, peptide-mimetics)
- Protein-protein interaction (immunoprecipitation, yeast two hybrid)
- Proteomics technology (protein identification and quantification, determining phosphorylation with MS)
- Cellomics technology (cellular high-content screening)
- Genome projects and the use of electronic databases (Entrez-based)
- Various examples from current research involving the above topics
Study Characteristics
- Discipline: Neurosciences
- Type of education: In class
- Academic skill: Research
- Graduate School: ONWAR: Graduate School Neurosciences Amsterdam Rotterdam (www.onwar.nl)
- Start date: bi-annual course, next course (maybe) in 2020, October
- End date: bi-annual course
- Minimum number of students: 15
- Maximum number of students: 40
- Admission criteria: PhD-students ONWAR (see also website ONWAR). External (neuroscience) PhD-students: fee is EUR 500. ONWAR-PhD-students always have priority.
- Concluding assessment: No
- With Certificate: Yes (for non-ONWAR-PhD-students)
- Schedule info: 5 days
- Number of lessons: N/A
- Total course duration in hrs.: N/A
- Sign up period: Continuously
- Anticipated hrs of study: N/A
- Available to: see admission criteria
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Course Objective & Study Characteristics
Course Objective
- General introduction to molecular biological principles
- Various quantification methods (e.g. quantitative PCR, Western blotting)
- Screening techniques (hybridization, micro arrays, SAGE, deep sequencing)
- Structure-function research (mutagenesis, 3D structure analysis)
- Genetic intervention studies (viral vectors, transgenesis, RNAi, peptide-mimetics)
- Protein-protein interaction (immunoprecipitation, yeast two hybrid)
- Proteomics technology (protein identification and quantification, determining phosphorylation with MS)
- Cellomics technology (cellular high-content screening)
- Genome projects and the use of electronic databases (Entrez-based)
- Various examples from current research involving the above topics
Study Characteristics
- Discipline: Neurosciences
- Type of education: In class
- Academic skill: Research
- Graduate School: ONWAR: Graduate School Neurosciences Amsterdam Rotterdam (www.onwar.nl)
- Start date: bi-annual course, next course (maybe) in 2020, October
- End date: bi-annual course
- Minimum number of students: 15
- Maximum number of students: 40
- Admission criteria: PhD-students ONWAR (see also website ONWAR). External (neuroscience) PhD-students: fee is EUR 500. ONWAR-PhD-students always have priority.
- Concluding assessment: No
- With Certificate: Yes (for non-ONWAR-PhD-students)
- Schedule info: 5 days
- Number of lessons: N/A
- Total course duration in hrs.: N/A
- Sign up period: Continuously
- Anticipated hrs of study: N/A
- Available to: see admission criteria
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