17 December 2021
Caitrin currently works at the AMC. By landing this Veni Grant she'll be joining the Receptor Biochemistry and Signaling group led by Prof. Dr. Martine Smit.
Cell biology relies on so-called ‘lock and key’ receptor-ligand interactions. But ‘keys’ (ligands) are not free-floating on their quest to find their ‘lock’ (receptor). Instead ’key-chains’ (decoys) hold them and dictate their freedom. I will investigate how these molecular key-chains control cell-migration in cancer, a process fundamental to disease progression.