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VERSION:2.0
PRODID:-//Vrije Universiteit Amsterdam//NONSGML v1.0//EN
NAME:PhD defense T. Priebe
METHOD:PUBLISH
BEGIN:VEVENT
DTSTART:20261111T154500
DTEND:20261111T171500
DTSTAMP:20261111T154500
UID:phd-defense-t-priebe@8F96275E-9F55-4B3F-A143-836282E12573
CREATED:20260925T005015
LOCATION:Main building VU, 1105, Auditorium, De Boelelaan, 1081 HV, Amsterdam
SUMMARY:PhD defense T. Priebe
X-ALT-DESC;FMTTYPE=text/html: Activity-Dependent A
daptations of Neuronal Secretory Vesicle Exocytosis
Brain
cells adjust their release of signaling substances during activity
Our brains must constantly maintain a good balance: ner
ve cells must be sufficiently active to transmit information, but not
so active that the network becomes disrupted. How brain cells mainta
in this balance is not yet fully understood. I studied how nerve cell
s adapt their communication when the activity in the network changes
for a long time.
My research shows that nerve cells ac
tively adapt their way of communicating when the activity in a brain
network decreases for a long time. I found that vesicles containing n
euromodulators – substances that affect the functioning of brain ce
lls – accumulate and are released more easily once activity increas
es again. This release appears to be necessary to strengthen the comm
unication between nerve cells and thus keep the network stable.
More information on the thesis to follow.
DESCRIPTION: Activity-Dependent Adaptations of Neuronal Secretory Vesi
cle Exocytosis Brain cells adjust their release of signaling subs
tances during activity
Our brains must constantly maintai
n a good balance: nerve cells must be sufficiently active to transmit
information, but not so active that the network becomes disrupted. H
ow brain cells maintain this balance is not yet fully understood. I s
tudied how nerve cells adapt their communication when the activity in
the network changes for a long time.My research shows that
nerve cells actively adapt their way of communicating when the activi
ty in a brain network decreases for a long time. I found that vesicle
s containing neuromodulators – substances that affect the functioni
ng of brain cells – accumulate and are released more easily once ac
tivity increases again. This release appears to be necessary to stren
gthen the communication between nerve cells and thus keep the network
stable.More information on the thesis to follow.
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