Long-Term Prognostic Perspectives of Cardiovascular Disease: Myocardium to Mind
< p>With the improved treatment of acute cardiovascular events and an a ging population, the global landscape of cardiovascular care is incre asingly shifting toward managing chronic cardiovascular disease. This transition is ongoing, as more patients live longer with the long-te rm consequences of cardiovascular disease. In addition, cardiovascula r disease may contribute to the development of cognitive impairment, another major public health concern. These chronic complications prof oundly impact quality of life and independence in daily life, while a lso placing a growing burden on healthcare systems, healthcare costs and society. This thesis addresses two challenges in the current age of cardiovascular care: (1) acute myocardial infarction (AMI) and its long-term complications, and (2) mechanisms through which cardiovasc ular disease may lead to abnormal brain aging and cognitive impairmen t. Using insights from cardiovascular magnetic resonance (CMR), this work aims to explore the underlying pathophysiological processes in d epth. The first part of this thesis focuses on identifying high-risk subgroups among patients with acute myocardial infarction to improve secondary prevention strategies. The second part examines the role of cardiovascular disease in the pathophysiology of cognitive impairmen t, with the aim of better understanding the complex interplay of card iac dysfunction, arterial stiffness, and vascular risk factors in the ir contribution to abnormal brain aging.More information on th e thesis
DESCRIPTION: Long-Term Prognostic Perspectives of Cardiovascular Disea se: Myocardium to Mind With the improved treatment of acute cardiovas cular events and an aging population, the global landscape of cardiov ascular care is increasingly shifting toward managing chronic cardiov ascular disease. This transition is ongoing, as more patients live lo nger with the long-term consequences of cardiovascular disease. In ad dition, cardiovascular disease may contribute to the development of c ognitive impairment, another major public health concern. These chron ic complications profoundly impact quality of life and independence i n daily life, while also placing a growing burden on healthcare syste ms, healthcare costs and society. This thesis addresses two challenge s in the current age of cardiovascular care: (1) acute myocardial inf arction (AMI) and its long-term complications, and (2) mechanisms thr ough which cardiovascular disease may lead to abnormal brain aging an d cognitive impairment. Using insights from cardiovascular magnetic r esonance (CMR), this work aims to explore the underlying pathophysiol ogical processes in depth. The first part of this thesis focuses on i dentifying high-risk subgroups among patients with acute myocardial i nfarction to improve secondary prevention strategies. The second part examines the role of cardiovascular disease in the pathophysiology o f cognitive impairment, with the aim of better understanding the comp lex interplay of cardiac dysfunction, arterial stiffness, and vascula r risk factors in their contribution to abnormal brain aging.More inf ormation on the thesis END:VEVENT END:VCALENDAR